Category: Cancer Research and Advances
Metformin Activates Tumor-Fighting T Cells in Mice, Suggesting Potential Role in Cancer Immunotherapy
Key Takeaways Metformin boosted CD8+ T cell activity in mice by increasing mitochondrial ROS and promoting immune cell growth. The anti-tumor effect wasn’t due to apoptosis, but to immune …Prostate Cancer MRI Scans May Underestimate Tumor Size: UCLA Study Warns of Treatment Risks
Key Takeaways: Prostate cancer is the second leading cause of cancer death in U.S. men, but early detection boosts survival rates to nearly 100%. Age, family history, and race …
Cancer Treatment: Nor-1 a Protein That Can Limit Heart Damage from Chemotherapy
Norwegian researchers have identified a protein called NOR-1 (Neuron-Derived Orphan Receptor 1) that has been shown to protect the heart from the cardiac side effects of chemotherapy. Read Also: …Researchers Say Cancer Immunotherapy Could Get a Boost from Reinvigorating Extremely Exhausted T Cells
The thinking used to be that when T cells get exhausted to a certain degree, they become practically useless and nothing can be done to salvage them. But new …
Inhibiting the Enzyme G6PD Destroys Metastatic Ovarian Cancer Cells in the Omentum
A team from the Los Angeles-based Terasaki Institute for Biomedical Innovation has identified the key role of a metabolic enzyme in ovarian cancer metastasis. The enzyme, glucose-6-phosphate dehydrogenase (G6PD), …Metformin and Syrosingopine: Diabetes and Blood Pressure Drugs Show Promise Against Cancer in Early Study
Key Takeaways: A drug pairing of metformin (diabetes medication) and syrosingopine (blood pressure drug) shows potential for starving cancer cells. The combo blocks two critical energy pathways cancer cells …
Chronic Stress and Obesity May Promote Pancreatic Cancer Growth via CREB Activation, Study Suggests
Key Takeaways Stress and obesity may contribute to pancreatic cancer: Both factors activate biological pathways that may accelerate tumor growth. Women may be more vulnerable: Hormonal differences could heighten stress-related …