Mesothelioma: Immunotherapy a Potential Alternative to Chemotherapy

Researchers have presented their findings in a Phase 3 trial showing that immunotherapy may be a viable alternative to chemotherapy for mesothelioma patients.

Lung X-Ray

Lung X-Ray

In the PROMISE-meso trial, scientists compared the efficacy of immunotherapy with pembrolizumab, a checkpoint inhibitor, against standard chemotherapy. They did this in mesothelioma patients who had relapsed after receiving first-line treatment. Their findings showed that these patients responded to immunotherapy, almost four times more.

Sadly, the observed greater responses failed to lead to a delay in the progression of the disorder or improved survival chances.

Read Also:  Warning! Talcum Powder Might Be Responsible for Mesothelioma a Rare Form of Cancer

“These findings are disappointing but, as in previous studies, some patients benefitted from immunotherapy for long periods,” said study author Dr. Sanjay Popat, of Royal Marsden Hospital NHS Foundation Trust in London, UK. “If we can find out how this happens, we will have a better idea of which patients should preferentially receive this treatment over chemotherapy.”

In spite of the mediocre results, Popat said that immunotherapy showed enough potential to serve as an alternative to chemotherapy.

Results from the PROMISE-meso trial were presented at the 2019 edition of the European Society of Medical Oncology (ESMO) annual meeting.



Want to Stay Informed?

Join the Gilmore Health News Newsletter!

Want to live your best life?

Get the Gilmore Health Weekly newsletter for health tips, wellness updates and more.

By clicking "Subscribe," I agree to the Gilmore Health and . I also agree to receive emails from Gilmore Health and I understand that I may opt out of Gilmore Health subscriptions at any time.