Researchers have been able to reduce the biological age of nine people by administering synthetic growth hormone injections (HGH) for 12 months.
A lot of research is being done around the world to rejuvenate body cells and slow down the aging process. One of them, published in the journal Cell Aging, suggests that a person’s biological clock can be set back a year and a half. A feat in the race against time.
Nine healthy men aged 51 to 65 took a synthetic growth hormone (HGH) to stimulate the thymus gland, a small gland located in the upper thorax between the lungs. The thymus gland plays an important role in the immune system, but atrophies with age and loses its effectiveness.
Reduction of the risk of mortality
Using blood samples taken before and after the experiment, researchers from the University of California found that the epigenetic age of the participants was reduced by one and a half years in 12 months of treatment. Epigenetics is the study of changes in gene activity: it measures the biological age of a person, i.e. the age of their cells, not their chronological age.
“This strongly suggests that their risk of mortality has decreased without us being able to give an accurate estimate of their life expectancy,” says Steve Horvath, Professor of Biostatistics and lead author of the study. However, this study, which was conducted only on white males in a single age group, needs to be conducted on a larger sample of people of different ages, ethnicity, and gender. A new trial with 50 participants is planned.
Rejuvenation of human cells
Recently, researchers at Stanford University succeeded in rejuvenating human cells with the help of proteins involved in the early stages of embryonic development and induced pluripotent stem cells, more simply called iPS (for “induced pluripotent stem cells”).
“When iPS cells are produced from adult cells, they become younger and pluripotent,” said Vittorio Sebastiano, assistant professor at Stanford University. For a while we wondered whether it would not be possible to simply stop the aging clock without inducing pluripotency”, i.e. the ability to reproduce. And “we succeeded,” said the researchers, who were able to rejuvenate the cells of several people.